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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 12.73
Human Site: T647 Identified Species: 23.33
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 T647 P L T P R R V T E V R A D T G
Chimpanzee Pan troglodytes XP_523371 1139 128318 T647 P L T P R R V T E V R A D T G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 S646 P L T P R R V S E V R A D T G
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 G644 P L T P R R V G E V R A D A G
Rat Rattus norvegicus O55081 1135 127799 G644 P L T P R R V G E V R T D A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 E591 R V T E V R A E T G G P G R S
Chicken Gallus gallus Q90600 921 104417 Y444 Q L G V R L Y Y R V M E S M L
Frog Xenopus laevis NP_001084880 998 113114 A521 E Q I L E S R A W T S D S V L
Zebra Danio Brachydanio rerio XP_002667000 970 107485 T493 A N T P S S K T E F S G N I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 P368 K Q D L P A Q P A M A G D K F
Honey Bee Apis mellifera XP_395096 1006 113492 Y529 N L D A Y Y F Y K V I E I I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 S558 H R C M L A C S A E L V V A T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 L536 M L A C S A E L V L A T H K T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 80 N.A. 13.3 20 0 26.6 N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 80 N.A. 20 20 0 33.3 N.A. 13.3 20 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 24 8 8 16 0 16 31 0 24 8 % A
% Cys: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 0 0 0 0 0 0 0 8 47 0 0 % D
% Glu: 8 0 0 8 8 0 8 8 47 8 0 16 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 16 0 8 8 16 8 0 39 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 8 0 8 16 0 % I
% Lys: 8 0 0 0 0 0 8 0 8 0 0 0 0 16 0 % K
% Leu: 0 62 0 16 8 8 0 8 0 8 8 0 0 0 16 % L
% Met: 8 0 0 8 0 0 0 0 0 8 8 0 0 8 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 39 0 0 47 8 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 8 16 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 47 47 8 0 8 0 39 0 0 8 0 % R
% Ser: 0 0 0 0 16 16 0 16 0 0 16 0 16 0 8 % S
% Thr: 0 0 54 0 0 0 0 24 8 8 0 16 0 24 16 % T
% Val: 0 8 0 8 8 0 39 0 8 54 0 8 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 8 16 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _